Publications/Conference Proceedings

Consultancy In Topical And Transdermal Drug Delivery

Book

Transdermal and Topical Drug Delivery - Principles and Practice. H. E. Benson and A. C. Watkinson (Eds.). Wiley. Published January 2012.

Book Chapters

  1. Watkinson AC, Hadgraft J, Street PR and Richards RW. Neutrons, surfaces and skin. In "Mechanisms of Transdermal Drug Delivery" by Russell O Potts and Richard H Guy (Eds.), Marcel Dekker p 231-265 (1997)
  2. Brain KR, Walters KA and Watkinson AC. Investigation of skin permeation in vitro. In "Dermal Absorption and Toxicity Assessment" by Michael S Roberts and Kenneth A Walters (Eds.), Marcel Dekker p 161-187 (1998)
  3. Brain KR, Watkinson AC and Walters KA. Reduction of the skin permeation of xenobiotics using chemical penetration retarders. In "NBC Risks. Current Capabilities and Future Perspectives for Protection" by Torsten Sohns and Victor A Voicu (Eds), Kluwer Academic Publishers p 271-277 (1999)
  4. Walters KA, Brain KR and Watkinson AC. Effects of protective clothing on the skin penetration of xenobiotics. In "NBC Risks" by Torsten Sohns and Victor A Voicu (Eds), Kluwer Academic Publishers p 293-301 (1999)
  5. Watkinson AC and Brain KR. Basic mathematical principles in skin permeation. In "Dermatological and Transdermal formulations" by Kenneth A Walters (Ed.), Marcel Dekker p 61-88 (2002)
  6. Brain KR, Walters KA and Watkinson AC. Methods for studying percutaneous absorption. In "Dermatological and Transdermal formulations" by Kenneth A Walters (Ed.), Marcel Dekker p 197-270 (2002)
  7. Wiechers JW and Watkinson AC. The influence of formulation type on skin delivery. In "Science and Applications of Skin Delivery Systems" by Johann J Wiechers (Ed.), Allured Publishing, Carol Stream, IL, USA p 61-90 (2008)
  8. Hadgraft J, Lane ME and Watkinson AC. Dermal and Transdermal Drug Delivery. In "Modified-Release Drug Delivery Technology" Second edition by Michael J Rathbone, Jonathan Hadgraft, Majella E Lane and Michael S Roberts (Eds.), Marcel Dekker p 271-280 (2008)
  9. Lane ME, Santos P, Watkinson AC and Hadgraft J. Passive skin permeation enhancement. In "Topical and Transdermal Drug Delivery - Principles and Practice" by HAE Benson and AC Watkinson (Eds.), John Wiley & Sons Inc. p 23-42 (2012)
  10. Watkinson AC. An overview of product development from concept to approval. In "Topical and Transdermal Drug Delivery - Principles and Practice" by HAE Benson and AC Watkinson (Eds.), John Wiley & Sons Inc. p 203-216 (2012)
  11. Watkinson AC. Transdermal and topical drug delivery today. In "Topical and Transdermal Drug Delivery - Principles and Practice" by HAE Benson and AC Watkinson (Eds.), John Wiley & Sons Inc. p 357-366 (2012)

Published Papers

  1. Watkinson AC, Hadgraft J and Bye A. Aspects of the transdermal delivery of prostaglandins Int. J. Pharm. 229-236, 74 (1991)
  2. Watkinson AC, Bunge AL and Hadgraft J. Aspects of the transdermal delivery of prostaglandins II. Int. J. Pharm. 171-175, 83 (1992)
  3. Watkinson AC, Bunge AL and Hadgraft J. Computer simulation of penetrant concentration-depth profiles in the stratum corneum. Int. J. Pharm. 175-182, 87 (1992)
  4. Watkinson AC, Brain KR, Walters, KA and Hadgraft, J. Prediction of the percutaneous penetration of ultra-violet filters used in sunscreen formulations. Int. J. Cosmetic Sci. 265-275, 14 (1992)
  5. Brain KR, Walters KA, Hadgraft J. and Watkinson AC. In vitro assessment of skin permeation from a transdermal system for the delivery of oestradiol. Int. J. Pharm. R13-R16, 89 (1993)
  6. Heard CM, Watkinson AC, Brain KR and Walters KA. In vitro skin penetration of propranolol enantiomers. Int. J. Pharm. R5-R8, 90 (1993)
  7. Watkinson AC, Brain BR, Walters KA and Hadgraft J. Investigation of relative rates of solvent and solute penetration through protective glove materials. Pesticide Science 251-256, 39 (1993)
  8. Watkinson AC and Walters KA. Cosmetically absorbing issues. Soap, Perfumery and Cosmetics 39-43, 67 (1994)
  9. Groundwater PW, Hadgraft J, Harrison JE and Watkinson AC. The synthesis of perdeuterated Azone (d-35-1-dodecylhexahydro-2H-azepin-2-one). J. Labelled Compounds and Radiopharmaceuticals 1047-1053, 34 (1994)
  10. Watkinson AC, Hadgraft J, Walters KA  and Brain KR. Measurement of diffusional parameters in membranes using ATR-FTIR. Int. J. Cosmetic Sci. 199-210, 16 (1994)
  11. Tralhaõ AML, Watkinson AC, Brain KR, Hadgraft J. and Armstrong NA. Use of ATR-FTIR spectroscopy to study the diffusion of ethanol through glycerogelatin films. Pharm. Res. 572-575, 12 (1995)
  12. Watkinson AC, Joubin H, Green DM, Brain KR and Hadgraft J. The influence of vehicle on permeation from saturated solutions. Int. J. Pharm. 27-36, 121 (1995)
  13. Lafforgue C, Eynard I, Falson F, Watkinson AC, Hadgraft J. Percutaneous absorption of methyl nicotinate. Int. J. Pharm. 89-93, 121 (1995)
  14. Roberts MS, Pugh WJ, Watkinson AC and Hadgraft J. Epidermal permeability-penetrant structure relationships: 1. An analysis of methods of predicting penetration of monofunctional solutes from aqueous solutions. Int. J. Pharm. 219-233, 126 (1995)
  15. Diez-Sales O, Watkinson AC, Herráez-Dominguez M, Javaloyes C and Hadgraft J. A mechanistic investigation of the in vitro human skin permeation enhancing effect of Azone®. Int. J. Pharm. 33-40, 129 (1996)
  16. Harrison JE, Watkinson AC, Green DM, Hadgraft J and Brain KR. The relative effect of Azone® and Transcutol® on permeant diffusivity and solubility in human stratum  corneum. Pharm. Res. 542-546, 13 (1996)
  17. Walters KA, Brain KR, Dressler WE, Green DM, Howes D, James VJ, Kelling CK, Watkinson AC and Gettings SD. Percutaneous penetration of N-Nitroso-N-Methyldodecylamine through human skin in vitro: application from cosmetic vehicles. Food & Chem. Toxicol. 705-712, 35 (1997)
  18. Pellett MA, Watkinson AC, Hadgraft J and Brain KR. Comparison of permeability data from traditional diffusion cells and ATR-FTIR spectroscopy. Part I Synthetic membranes. Int. J. Pharm. 205-215, 154 (1997)
  19. Pellett MA, Watkinson AC, Hadgraft J and Brain KR. Comparison of permeability data from traditional diffusion cells and ATR-FTIR spectroscopy. Part II Determination of diffusional pathlengths in synthetic membranes and human stratum corneum. Int. J. Pharm. 217-227, 154 (1997)
  20. Walters KA, Brain KR, Green DM, James, VJ, Watkinson AC and Sands RH. Comparison of the transdermal delivery of estradiol from two gel formulations. Maturitas 189-195, 29 (1998)
  21. Walters KA, Watkinson AC and Brain KR. In vitro skin permeation evaluation; the only realistic option. Int. J. Cosmetic Sci. 307-316, 29 (1998)
  22. Watkinson AC and Brain KR. Boosting the skin's barrier function. Soap, Perfumery & Cosmetics 49-54 (1998)
  23. Watkinson AC. Developments in contraceptive transdermal patch technology. European Pharmaceutical Contractor, 52-56 (August 1999)
  24. Walters KA, Brain KR, Howes D, James VJ, Kraus AL, Teetsel NM, Toulon M, Watkinson AC and  Gettings SD. Percutaneous penetration of octyl salicylate from representative sunscreen formulations through human skin in-vitro. Food Chem. Toxicol. 1219-1225, 35 (1997)
  25. Watkinson AC. The pharmacokinetics of drug delivery systems in hormone replacement therapy. J. Brit. Menopause Soc. 105-108, 7 (2001)
  26. Watkinson AC and Brain KR. Basic mathematical principles in skin permeation. J. Tox. Cut. Ocu. Tox. 371-402, 21 (2002)
  27. Bird DK, Schneider AL, Watkinson AC, Finnin B and Smith TA. Navigating transdermal diffusion with multiphoton fluorescence lifetime imaging. J. Microscopy. 61-69, 230 (2008)
  28. Santos P, Watkinson AC, Hadgraft J and Lane ME. Application of microemulsions in dermal and transdermal drug delivery. Skin Pharmacology and Physiology, 246-259, 21 (2008)
  29. Santos P, Machado M, Watkinson AC, Hadgraft J and Lane ME. The effect of drug concentration on solvent activity in silicone membranes. Int. J. Pharm. 70-75, 377 (2009)
  30. Chilcott RP, Barai N, Beezer AE, Brain SI, Brown MB, Bunge AL, Burgess SE, Cross S, Dalton CH, Dias M, Farinha A, Finnin BC, Gallagher SJ, Green DM, Gunt H, Gwyther RL, Heard CM, Jarvis CA, Kamiyama F, Kasting GB, Ley EE, Lim ST, McNaughton GS, Morris A, Nazemi MH, Pellett MA, Du Plessis J, Quan YS, Raghavan SL, Roberts M, Romonchuk W, Roper CS, Schenk D, Simonsen L, Simpson A, Traversa BD, Trottet L, Watkinson A, Wilkinson SC, Williams FM, Yamamoto A, Hadgraft J. Inter- and intra-laboratory variation of in vitro diffusion cell measurements: An international multicenter study using quasi-standardized methods and materials. J. Pharm. Sci. 632-638, 94 (2005)
  31. Santos P, Watkinson AC, Hadgraft J and Lane ME. Oxybutynin permeation in skin: The influence of drug and solvent activity. Int. J. Pharm.  67-72 384 (2010)
  32. Santos P, Watkinson AC, Hadgraft J and Lane ME. Formulation issues associated with transdermal febtanyl delivery. Int J. Pharm. 155-159 416 (2011)
  33. Santos P, Watkinson AC, Hadgraft J and Lane ME. Enhanced permeation of fentanyl from supersaturated solutions in a model membrane. Int. J. Pharm. 72-77 407 (2011)
  34. Wang C, Ilani N, Arver S, McLachlan RI, Soulis T and Watkinson AC. Efficacy and safety of a 2% formulation of testosterone topical solution applied to the axillae in androgen-deficient men. Clin Endocrinol. 836-843 75 (2011)
  35. Gee CM, Nicolazzo JA, Watkinson AC and Finnin BC. Assessment of the lateral diffusion and penetration of topically applied drugs in humans using a novel concentric tape stripping design. Pharm. Res. 2035-2046 29 (2012)
  36. Santos P, Watkinson AC, Hadraft J and Lane ME. Influence of penetration enhancer on drug permeation from volatile formulations. 439 260-268 (2012)
  37. Wiechers JW, Watkinson AC, Cross SE and Roberts MS. Predicting skin penetration of actives from complex cosmetic formulations: an evaluation of inter formulation and inter active effects during formulation optimization for transdermal delivery. Int. J. Cos. Sci. 34 525-535 (2012)
  38. Watkinson AC, Bunge AL, Hadgraft J and Lane ME. Nanoparticles do not penetrate human skin - a theoretical perspective. Pharm. Res. 1943-1946 30 (2013).
  39. Watkinson AC. A commentary on transdermal drug delivery systems in clinical trials. J. Pharm Sci. 3082-3088 102 (2013).
  40. Anissimov YG and Watkinson AC. Modelling skin penetration using the Laplace transform technique. Skin Pharmacol. Physiol. 286-294 26 (2013).
  41. Gee CM, Watkinson AC, Nicolazzo JA and Finnin BC. The effect of formulation excipients on the penetration and lateral diffusion of ibuprofen on and within the stratum corneum following topical application to humans. J. Pharm. Sci. 103 909-919 (2014).
  42. Watkinson AC, Kearney M, Quinn, H, Courtenay A and Donnelly R. Future of the transdermal drug delivery market - have we barely touched the surface? Exp. Opin. Drug Deliv. 523-532 13 (2016)

Conference Proceedings

  1. Watkinson AC, Hadgraft J and Bye A. Enhanced penetration of prostaglandin E2 through human skin in-vitro. J. Pharm. Pharmcol. 42, (Supplement) (1990) 86P
  2. Watkinson AC, Street PR, Richards RW and Hadgraft J. Evidence for phase separation of oleic acid in DPPC liposomes and excised stratum corneum from a small angle neutron scattering (SANS) study. In "Prediction of percutaneous penetration", volume 2, IBC Technical Services, Scott RC, Guy RH, Hadgraft J and Bodde H (Eds.) p 380-385 (1991)
  3. Watkinson AC and Hadgraft J. Small angle neutron scattering (SANS) studies on DPPC/Azone® multilamellar systems. In "Proceedings of the 1st Annual UKAPS Conference", Hadgraft J, Kellaway I and Parr G. (Eds.) p 16 (1992)
  4. Watkinson AC, Brain KR and Walters KA. The penetration of ibuprofen through human skin in vitro: use of differing physicochemical properties of racemate and pure enantiomers to 'enhance' absorption from saturated solutions. In "Prediction of Percutaneous Penetration", volume 3a, STS Publishing Ltd, Cardiff. Brain KR, Hadgraft J, James VJ and Walters KA (Eds.) C1 (1993)
  5. Watkinson AC, Brain KR and Walters KA. The penetration of ibuprofen through human skin in-vitro in the presence of Azone®: vehicle and pH effects. In "Prediction of Percutaneous Penetration", volume 3a, STS Publishing Ltd, Cardiff. Brain KR, Hadgraft J, James VJ and Walters KA (Eds.) C3 (1993)
  6. Heard CM, Watkinson AC and Brain KR. Is transfer of propranolol enantiomers across rat skin an enantioselective process? In "Prediction of Percutaneous Penetration", volume 3a, STS Publishing Ltd, Cardiff. Brain KR, Hadgraft J, James VJ and Walters KA (Eds.) C4 (1993)
  7. Brain KR, Curtis L, Hadgraft J, James VJ, Walters KA, Wong WCF and Watkinson AC. In-vitro testing of efficacy of protective glove materials on skin permeation of xenobiotics: occlusion and reservoir effects. In "Prediction of Percutaneous Penetration", volume 3a, STS Publishing Ltd, Cardiff. Brain KR, Hadgraft J, James VJ and Walters KA (Eds.) C100 (1993)
  8. Watkinson AC, Brain KR and Walters KA. The penetration of ibuprofen through human skin in-vitro: vehicle, enhancer and pH effects. In "Prediction of Percutaneous Penetration", volume 3b, STS Publishing Ltd, Cardiff. Brain KR, Hadgraft J, James VJ and Walters KA (Eds.) p 335-341 (1993)
  9. Watkinson AC, Brain KR and Walters KA. The percutaneous penetration of ibuprofen : use of the differing physicochemical properties of racemate and pure enantiomers to 'enhance' absorption from saturated solutions. In "Prediction of Percutaneous Penetration", volume 3b, STS Publishing Ltd, Cardiff. Brain KR, Hadgraft J, James VJ and Walters KA (Eds.) p 342-345 (1993)
  10. Heard CM, Watkinson AC and Brain KR. Transfer of propranolol enantiomers across skin:  Is the process enantio-selective? In "Prediction of Percutaneous Penetration", volume 3b, STS Publishing Ltd, Cardiff. Brain KR, Hadgraft J, James VJ and Walters KA (Eds.) p 346-353 (1993)
  11. Sarphie DF, Bellhouse BJ, Alexander Y, Brain KR, Walters KA and Watkinson AC. Gas propulsion of microprojectiles for transdermal delivery of powder form drugs. In "Prediction of Percutaneous Penetration", volume 3b, STS Publishing Ltd, Cardiff. Brain KR, Hadgraft J, James VJ and Walters KA (Eds.) p 360-368 (1993)
  12. Brain KR,  Curtis L, Hadgraft J, James VJ, Walters KA, Watkinson AC and Wong WCF. Assessment of efficacy of protective glove materials: significance of occlusion and reservoir effects. In "Prediction of Percutaneous Penetration", volume 3b, STS Publishing Ltd, Cardiff. Brain KR, Hadgraft J, James VJ and Walters KA (Eds.) p 604-608 (1993)
  13. Watkinson AC, Brain KR and Walters KA. Skin penetration of cosmetic ingredients - predictive methods  and  risk assessment. In "Biocosmetics - skin aging", volume II. Proceedings of the IFSCC conference (Platja d'Aro, Spain) p 109 - 122 (1993)
  14. Walters KA, Brain KR and Watkinson AC. Effects of surfactants and solvents on human skin permeation. Society of Toxicology Annual Meeting, Dallas, p 342 (1994)
  15. Pellett MA, Watkinson AC, Hadgraft J and Brain KR. An investigation into the interaction of propylene glycol/water vehicles with polydimethylsiloxane. Proceedings of the 3rd annual UKaps conference, Leicester. Hadgraft J, Kellaway IW and Parr GD (Eds.) p 31 (1994)
  16. Watkinson AC, Pellett MA, Hadgraft J and Brain KR. Diffusional parameters by ATR-FTIR spectroscopy. Proceedings of the 3rd annual UKaps conferene, Leicester. Hadgraft J, Kellaway, IW and Parr, GD (Eds.) p 75 (1994)
  17. Walters KA, Brain KR and Watkinson AC. Influence of dodecyl based surfactants and solvents on human skin permeation. Proceedings of the 13th Pharmaceutical Technology Conference, Strasbourg, France, Volume 2a, p 740-746 (1994)
  18. Pellett MA, Watkinson AC, Hadgraft J and Brain KR. Diffusion of deuterated ethanol in synthetic membranes using ATR-FTIR spectroscopy. Eur. J. Pharm. Sci. P147, p 155, 2, (1994)
  19. Watkinson AC, Hadgraft J and Brain KR. The use of in-vitro ATR-FTIR for the assessment of synthetic and skin membrane diffusional parameters. 10th International Symposium on Bioengineering and the Skin, Cincinnati, Ohio, USA, P44 (1994)
  20. Watkinson AC, Hadgraft J, and Brain KR. The deconvolution of diffusion and partition coefficients in permeability studies. Proceedings of the 21st International Symposium on Controlled Release of Bioactive Materials (Nice, France) p 160-161 (1994)
  21. Walters KA, Watkinson AC, Walters EJ and Brain KR. Influence of post-application treatment on skin permeation of the sunscreen PABA. Proceedings of the 21st International Symposium on Controlled Release of Bioactive Materials (Nice, France) p 419-420 (1994)
  22. Pellet MA, Watkinson AC, Hadgraft J and Brain KR. An ATR-FTIR investigation of the interactions between vehicles and a synthetic membrane. Proceedings of the 21st International Symposium on Controlled Release of Bioactive Materials (Nice, France) p439-440 (1994)
  23. Heard CM, Watkinson AC and Brain KR. Mechanisms and implications of differential percutaneous permeation of chiral drugs. Proceedings of the 21st International Symposium on Controlled Release of Bioactive Materials (Nice, France) p447-448 (1994)
  24. Watkinson AC, Hadgraft J, Walters KA  and Brain KR. In-vitro measurement of diffusional parameters in silastic membranes and human skin using ATR-FTIR Spectroscopy. Proceedings of the 18th IFSCC conference, (Venezia, Italy) P102 p 889-901 (1994)
  25. Tralhao AM, Watkinson AC, Brain KR, Hadgraft J and Armstrong NA. Measurement of diffusion of ethanol through glycerogelatin films by ATR-FTIR spectroscopy. Eur. J. Pharm. Sci. 2, P146, p 155 (1994)
  26. Brain KR, James VJ and Watkinson AC. Determination of the percutaneous penetration of essential oil components used in aromatherapy. Proceedings of the 25th International Symposium Essential Oils (Grasse, France) O-15 (1994)
  27. Watkinson AC, Walters KA, Brain KR, James VJ, Dressler WE, Howes D, Kelling CK Gettings SD. Comparison of the in vitro human skin penetration of three nitrosamines. The Toxicologist 1726, p 322, 15, (1995)
  28. Watkinson AC, Joubin H, Green DM, Brain KR and Hadgraft J. Simultaneous measurement of permeant and vehicle permeation in the assessment of vehicle effects on membrane penetration. In "Prediction of Percutaneous Penetration", volume 4a, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds.) C2 (1995)
  29. Brain KR, Green DM, James VJ, Walters KA, Watkinson AC, Allan G and Hammond J. Preliminary evaluation of novel penetration retarders. In "Prediction of Percutaneous Penetration", volume 4a, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds.) C38 (1995)
  30. Watkinson AC, Green DM, Hadgraft J Walters KA and Brain KR. Towards the "retro-formulation" of a weak acid. In "Prediction of Percutaneous Penetration", volume 4a, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds.), C66 (1995)
  31. Pellett MA, Watkinson AC, Brain KR and Hadgraft J. An investigation into the validity of deuterated labelling of compounds in relation to their diffusion within synthetic membranes. Procedings of the 4th annual UKaps conference, Nottingham. Hadgraft J and Kellaway IW (Eds.) p 68 (1995)
  32. Watkinson AC, Joubin H, Green DM, Brain KR and Hadgraft J. Vehicle/membrane interactions in permeability studies I. Proceedings of the 22nd International Symposium on Controlled Release of Bioactive Materials (Seattle, USA) p 642-643 (1995)
  33. Watkinson AC, Joubin H, Green DM, Brain KR and Hadgraft J. Vehicle/membrane interactions in permeability studies II. Proceedings of the 22nd International Symposium on Controlled Release of Bioactive Materials (Seattle, USA), 644-645 (1995)
  34. Watkinson AC, Joubin H, Green DM, Brain KR and Hadgraft J. Simultaineous measurement of permeant and vehicle permeation in the assessment of vehicle effects on membrane permeation. In "Prediction of Percutaneous Penetration", volume 4b, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds.) 34-37 (1996)
  35. Brain KR, Green DM, James VJ, Walters KA, Watkinson AC, Allan G and Hammond J. Preliminary evaluation of novel penetration retarders. In "Prediction of Percutaneous Penetration", volume 4b, STS Publishing Ltd, Cardiff. Brain KR, James, VJ and Walters KA (Eds.) 131-132 (1996)
  36. Watkinson AC, Green DM, Hadgraft J, Walters KA and Brain KR. Towards the "retro-formulation" of a weak acid. In "Prediction of Percutaneous Penetration", volume 4b, STS Publishing Ltd, Cardiff. Brain KR, James, VJ and Walters KA (Eds.) 174-177 (1996)
  37. Walters KA, Watkinson AC, Green DM, Brain KR, Azri-Meehan S, Sharma RK and Dressler WE. In vitro skin permeation of a homologous series of nonoxynols. The Toxicologist 1646, p 324, 36, (1997)
  38. Sharma RK, Dressler WE, Grabarz R, Watkinson AC, Green DM and Walters KA. In vitro skin permeation of para-phenyldiamine (PPD). The Toxicologist, 1647, p 324 36, (1997)
  39. Pellett MA, Watkinson AC, Hadgraft J and Brain KR. Evaluation of ATR-FTIR spectroscopy for the measurement of diffusion coefficients of permeants in rate-limiting membranes. J. Pharm. Pharmacol. 150, p 83, 49, Supplement 4, (1997)
  40. Pellett MA Watkinson AC, Brain KR and Hadgraft J. Evaluation of diffusion coefficients in silicone membrances using ATR-FTIR spectroscopy and concentration-depth profiles. Pharm. Res. 1107, S-36 14, (1997)
  41. Dressler WE, Grabarz R, Sharma R, Brain KR, Green DM, James VJ, Walters KA and Watkinson AC. Percutaneous penetration of oxidative hair dyes from human cadaver skin, in-vitro. In "Perspectives in Percutaneous Penetration", volume 5a, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds.) 21 (1997)
  42. Watkinson AC, Green DM, Brain KR, James VJ, Walters KA, Azri-Meehan S, Sharma R and Dressler W. Nonoxynols: skin penetration of a series of homologues. In "Perspectives in Percutaneous Penetration", volume 5a, STS Publishing Ltd, Cardiff. Brain KR, James, VJ and Walters, KA (Eds.) 22 (1997)
  43. Howes D, Watkinson AC, Walters KA and Brain KR. A more complete approach to the modelling of dermal risk assessment.In "Perspectives in Percutaneous Penetration", volume 5a, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds) 27 (1997)
  44. Pellett MA, Watkinson AC, Brain KR and Hadgraft J. Correlation of permeability and morphology of the distal and proximal regions of the stratum corneum. In "Perspectives in Percutaneous Penetration", volume 5a, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds.) 32 (1997)
  45. Green DM, James VJ and Watkinson AC. Effect of exposure conditions and tape type on the efficiency of in-vitro tape stripping. In "Perspectives in Percutaneous Penetration", volume 5a, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds.) 50 (1997)
  46. Pellett MA, Watkinson AC, Brain KR and Hadgraft J. Diffusion of flurbiprofen across human stratum corneum using synergistic methods of enhancement. In "Perspectives in Percutaneous Penetration", volume 5a, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds.) 86 (1997)
  47. Pellett, M.A., Watkinson, A.C., Brain, K.R. and Hadgraft, J. Effects of ethanol on the diffusion and partition coefficients of 4-cyanophenol in silicone membranes. In "Perspectives in Percutaneous Penetration", volume 5a, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds.) 87 (1997)
  48. Watkinson AC, Pellett MA, Brain KR and Hadgraft J. In-vitro/in-vivo comparison of skin permeability using ATR-FTIR spectroscopy. In "Perspectives in Percutaneous Penetration", volume 5a, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds.) 129 (1997)
  49. Watkinson AC, Pellett MA, Brain KR and Hadgraft J. Measurement of diffusional pathlengths using diffusion cells and ATR-FTIR spectroscopy. Part 1 - Silicone membranes. Proceedings of the 24th International Symposium on Controlled Release of Bioactive Materials (Stockholm, Sweden) p19-20 (1997)
  50. Watkinson AC, Pellett MA, Brain KR and Hadgraft J. Measurement of diffusional pathlengths using diffusion cells and ATR-FTIR spectroscopy. Part 2 - Stratum corneum. Proceedings of the 24th International Symposium on Controlled Release of Bioactive Materials (Stockholm, Sweden) p699-700 (1997)
  51. Watkinson AC, Green DM, Brain KR, James VJ, Walters KA, Azri-Meehan S, Sharma R and Dressler W. Skin penetration of a series of nonoxynol homologues. In "Perspectives in Percutaneous Penetration", volume 5B, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds.) 54-59 (1997)
  52. Howes D, Watkinson AC, and Brain KR. A more complete approach to the modelling of dermal risk assessment. In "Perspectives in Percutaneous Penetration", volume 5B, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds.) 68-69 (1997)
  53. Green DM, James VJ and Watkinson AC. The influence of exposure conditions and the type of tape on the efficiency of tape stripping in-vitro. In "Perspectives in Percutaneous Penetration", volume 5B, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds.) 108-109 (1997)
  54. Pellett MA, Watkinson AC, Brain KR and Hadgraft J. Effects of ethanol on the diffusion and partition coefficients of 4-cyanophenol in silicone membranes. In "Perspectives in Percutaneous Penetration", volume 5B, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds.) 169-172 (1997)
  55. Pellett MA, Watkinson AC, Brain KR and Hadgraft J. Synergism between supersaturation and chemical enhancement in the permeation of flurbiprofen through human skin. In "Perspectives in Percutaneous Penetration", volume 5B, STS Publishing Ltd, Cardiff. Brain KR, James, VJ and Walters KA (Eds.) 173-176 (1997)
  56. Morris A, Kee WJ, Brain KR, Heard CM and Watkinson AC. Vehicle effects in the permeation of primaquine across human skin in vitro. In "Perspectives in Percutaneous Penetration", volume 5B, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds.) 180-182 (1997)
  57. Allender CJ, Brain KR, Watkinson AC, Heard CM. Development of controlled transdermal delivery devices using molecularly imprinted polymers. In "Perspectives in Percutaneous Penetration", volume 5B, STS Publishing Ltd, Cardiff. Brain KR, James, VJ and Walters, KA (Eds.) 183-185 (1997)
  58. Pellett MA, Watkinson AC, Brain KR and Hadgraft J. Correlation of permeability and morphology of the distal and proximal regions of the stratum corneum. In "Perspectives in Percutaneous Penetration", volume 5B, STS Publishing Ltd, Cardiff. Brain KR, James, VJ and Walters, KA (Eds.), 273-275 (1997)
  59. Pellett MA, Watkinson AC, Brain KR and Hadgraft J. Comparison of measurement of skin permeability using ATR-FTIR spectroscopy in-vitro and in-vivo. In "Perspectives in Percutaneous Penetration", volume 5B, STS Publishing Ltd, Cardiff. Brain KR, James VJ and Walters KA (Eds.), 276-277 (1997)
  60. Wiechers JW and Watkinson AC. Influence of penetrant and formulation type on dermal and transdermal delivery. In "Perspectives in Percutaneous Penetration", volume 6a, STS Publishing Ltd, Cardiff. Brain KR and Walters KA (Eds.) 24 (1998)
  61. Watkinson AC, Green DM, Brain KR, Walters KA and Van der Wilden W. Restoration of skin barrier function by application of lipid mixtures containing biotechnologically-derived ceramides. In "Perspectives in Percutaneous Penetration", volume 6a, STS Publishing Ltd, Cardiff. Brain KR and Walters KA (Eds.) 37 (1998)
  62. Watkinson AC, Brain KR, Walters KA, Grabarz RS and Sharma RK. Is it logical to reject skin samples based on water permeability data? In "Perspectives in Percutaneous Penetration", volume 6a, STS Publishing Ltd, Cardiff. Brain KR and Walters KA (Eds.) 62 (1998)
  63. Brain KR, Green DM, James VJ, Sands RH, Walters KA and Watkinson AC. Complexities in the comparison of percutaneous penetration of estradiol from gel formulations with different dose levels and application recommendations. In "Perspectives in Percutaneous Penetration", volume 6a, STS Publishing Ltd, Cardiff. Brain KR and Walters KA (Eds.) 80 (1998)
  64. Brain KR, Dressler WE, Gettings SD, Green DM, Sharma RK, Walters KA and Watkinson AC. Importance of appropriate study design and data interpretation in the estimation of dermal protection afforded by glove materials. In "Perspectives in Percutaneous Penetration", volume 6a, STS Publishing Ltd, Cardiff. Brain KR and Walters, KA (Eds.) 104 (1998)
  65. Sharma RK, Dressler WE, Grabarz RS, Brain KR, Watkinson AC and Walters KA. Correlation of in vitro percutaneous absorption data for hair dyes with in vivo data. In "Perspectives in Percutaneous Penetration", volume 6a, STS Publishing Ltd, Cardiff, Brain KR and Walters, KA (Eds.) 110 (1998)
  66. Beck H, Brain K, Dressler W, Grabarz R, Green D, Howes D, Kitchiner L, Pendlington R, Python M, Schroder K, Sharma R, Steiling W, Sugimoto K, Walters K and Watkinson A. An interlaboratory/interspecies comparison of percutaneous penetration of 14C-phenylenediamine (PPD) from a hairdye formulation, in vitro. In "Perspectives in Percutaneous Penetration", volume 7a, STS Publishing Ltd, Cardiff. Brain KR and Walters KA (Eds.) 27 (2000)
  67. Rashid MH, Bonner MC, Barry BW, Brain KR and Watkinson AC. Iontophoresis of L-glutamic acid across human epidermal membrane: effects of current density and membrane hydration. In "Perspectives in Percutaneous Penetration", volume 7a, STS Publishing Ltd, Cardiff. Brain KR and Walters, KA (Eds.) 111 (2000)
  68. Brain KR, Brain S, Green, DM, Walters KA, Watkinson AC, Alcasey S, Blackburn K, Brock W, Burdick J, Davis D, Dressler W, Driedger A, Fung W, Gettings S, Mann S, Re T and Rios-Blanco M. Penetration and distribution of diethanolamine through human skin in-vitro after application from cosmetic vehicles under in-use conditions. In "Perspectives in Percutaneous Penetration", volume 8a, STS Publishing Ltd, Cardiff, Brain KR and Walters, KA (Eds.) 101 (2002)
  69. Watkinson AC, Delahaye HD and Vickers J. Transdermal delivery of methylphenidate using Matriderm adhesive. Proceedings of the 29th International Symposium on Controlled Release of Bioactive Materials (Seoul, South Korea) No. 459 (2002)
  70. Watkinson AC. Multidiscipliary approach to the development of skin products. J. Pharm. Pharmacol. 56, S107, 310 (2004)
  71. Watkinson AC. Non-occlusive transdermal drug delivery from a spray - from concept to product. Skin Forum (2009)
  72. Vieira R, Lane ME, Hadgraft J, Anissimov Y, Watkinson AC. Modeling of drug permeation in human skin in vitro from finite dose applications. Skin Forum (2010).
  73. Gee CM, Nicolazzo JA, Watkinson AC and Finnin BC. Penetration and lateral diffusion of caffeine, hydrocortisone and ibuprofen following topical application of ethanolic solutions to humans. Australian Pharmaceutical Society Conference, Brisbane (2010)
  74. Marjason J, Watkinson AC and Soulis T. Evaluation of the amount of residual Testosterone MD-Lotion® 2% (testosterone solution 2%) remaining on the underarm in healthy males who undergo a post-dose washing procedure. American Society of Andrology (2011).
  75. Marjason J, Watkinson AC and Soulis T. Impact of antiperspirant and deodorant as well as washing the application site, on the pharmacokinetics of testosterone following single dose applications of 2% Testosterone MD-Lotion® (testosterone solution 2%). American Society of Andrology (2011).